butabarbital will minimize the extent or influence of midazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

butabarbital will minimize the extent or influence of estrogens esterified by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

If mixed, dose reduction or discontinuation of a number of CNS depressants (including the oxybate salt product or service) need to be regarded as. Interrupt oxybate salt therapy through shorter-expression opioid use Consider therapy modification

butabarbital will lower the extent or effect of vardenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

butabarbital will decrease the level or effect of vinblastine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.

Keep an eye on Carefully (1)butabarbital will lessen the extent or influence of cannabidiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

Anticoagulant dose decreases may very well be needed subsequent barbiturate discontinuation or dose reduction. Consider therapy modification

butabarbital will lessen the level or outcome of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

However, the serial serum pentobarbital concentrations and correlation Along with the clinical status are noteworthy, Particularly time class to medical recovery.

butabarbital will lessen the extent or influence of ivosidenib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of ivosidenib with strong CYP3A4 inducers diminished ivosidenib plasma concentrations.

buprenorphine, extensive-acting injection and butabarbital Butabarbital Sodium both boost sedation. Stay away from or Use Alternate Drug. Limit use to people for whom choice treatment possibilities are inadequate

Barbiturates don't impair standard hepatic purpose, but are already proven to induce liver microsomal enzymes, So growing and/or altering the metabolism of barbiturates along with other medicines (see Safeguards-DRUG INTERACTIONS).

butabarbital will lessen the extent or outcome of tamoxifen by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

butabarbital will lower the level or effect of buspirone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.